WebOur lab seeks to discover drug targets by applying genetic screens to human cancer cells. This genetic screening campaign has overwhelmingly led us to DNA-binding transcription … WebAU - Vakoc, Christopher R. N1 - Funding Information: We would like to thank all members of the C.R.V. and D.A.T. laboratories for helpful discussions and suggestions throughout the course of this study. The authors would like to thank the Cold Spring Harbor Cancer Center Support Grant (CCSG, P30CA045508-29) shared resources: Bioinformatics ...
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WebJan 6, 2014 · Christopher R. Vakoc J.S. Roe and C.R. Vakoc are at the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724. CORRESPONDENCE C.R.V.: [email protected]. Search for other works by this author on: This Site. PubMed. Google Scholar. Author and Article Information Jae-Seok Roe ... WebSep 9, 2011 · During the course of this research, a collaborative effort with the laboratories of Christopher Vakoc and Scott Lowe revealed BRD4 as a tumor dependency in acute myeloid leukemia. Consistent with our observations described here in MM, leukemia cells similarly require BRD4 to sustain MYC expression to enforce aberrant self-renewal ( … strainer vs stretcher
An epigenetic fulcrum tipped in cancer
WebChristopher R. Vakoc Small cell lung cancer (SCLC) is widely considered to be a tumor of pulmonary neuroendocrine cells; however, a variant form of this disease has been described that lacks ... WebChristopher Vakoc Profile page. Orcid identifier 0000-0002-1158-7180. Professor. Vakoc Laboratory. Program Co-Leader. Cancer Center. Faculty Head, Functional Genomics … WebApr 24, 2024 · Christopher R Vakoc , Cold Spring Harbor Laboratory, United States; ... (MAB275-100; R and D Systems) or IgG2B isotype control (MAB004; R and D Systems) … strainer water