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Functional Roles of p38 Mitogen-Activated Protein Kinase
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Octreotide-Paclitaxel Conjugate Reverses Paclitaxel Resistance by p38 …
WebThe mitogen-activated protein kinase p38 (MAPK p38) has emerged as an attractive target for the treatment of inflammatory disorders. This kinase plays a key role in the regulation of inflammatory cytokine production since MAPK p38 inhibitors have been demonstrated to reduce levels of the T H1 -type cytokines TNF-α and IL1, both in vitro and in ... WebThe p38 mitogen-activated protein kinase (MAPK) pathway, initially described as a transducer of the response to environmental stress conditions, plays an important role in skeletal muscle differentiation. WebApr 29, 2015 · Summary. Non-essential amino acid L-glutamine (Gln) possesses anti-inflammatory activity via deactivating cytosolic phospholipase A 2 (cPLA 2).We showed previously that Gln deactivated cPLA 2 indirectly via dephosphorylating p38 mitogen-activated protein kinase (MAPK), the major kinase for cPLA 2 phosphorylation, through … hellbound train: an anthology