Slc11a1 rs4674301

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August undefined, 2024

WebApr 12, 2024 · Europe PMC is an archive of life sciences journal literature. Age- and gender-dependent association of SLC11A1 polymorphisms with tuberculosis susceptibility WebSLC11A1, located on the human chromosome 2q35, is an important regulator of macrophage responses to MTB (McHenry et al., 2024). Genetic variants of SLC11A1 have …

c-Src kinase is involved in the tyrosine phosphorylation and …

WebMar 9, 2024 · The Slc11a1 encodes a late endosomal/lysosomal protein/divalent cation transporter, which regulates iron homeostasis in macrophages. results demonstrate a role for Slc11a1 (Nramp1) in modifying susceptibility to type 1 diabetes and illustrate that RNAi can be used to study causal genes in a mammalian model organism WebThis gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions … clothotk address

INFECTION Host resistance factor SLC11A1 restricts …

WebJan 1, 2009 · Slc11a1 is proinflammatory, but it is not clear whether Slc11a1 directly affects the production of inflammatory cytokines by DCs and macrophages or through indirect … WebSSC1S311A is the controller IC of a quasi-resonant mode for a switching power supplies. The IC incorporates a startup circuit and a standby function to reduce a power … Web10 kt semi solid braclet. Ships to you. $8. Vintage Copper Revere Ware Tea Kettle. Indianapolis, IN. $20. 10 kt semi solid braclet. Ships to you. $20. clotho the fate

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WebThis meta-analysis suggests that polymorphisms in the SLC11A1 gene contribute to TB (both PTB and EPTB), particularly in Asians. BACKGROUND Polymorphisms in SLC11A1 gene have been extensively studied for an association with tuberculosis (TB); however, results from replication studies have been inconsistent. OBJECTIVE To comprehensively … WebSLC11A1 INFORMATION. Proteini. Full gene name according to HGNC. Solute carrier family 11 member 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. SLC11A1 (LSH, NRAMP, NRAMP1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). bytefence scanWebSearch Partnumber : Match&Start with "SSC1S311A" - Total : 1 ( 1/1 Page) Manufacturer. Part No. Datasheet. Description. Sanken electric. SSC1S311A. 1Mb / 28P. Quasi-Resonant … bytefence scam how to remove

"WebMay 3, 2024 · Studies have demonstrated that the solute carrier family 11 member 1 (SLC11A1) is heavily glycosylated and phosphorylated in macrophages. However, the mechanisms of SLC11A1 phosphorylation, and the effects of phosphorylation on SLC11A1 activity remain largely unknown. Here, the tyrosine phosphorylation of SLC11A1 is … " - Slc11a1 rs4674301

Slc11a1 rs4674301

WebSep 21, 2009 · Background The etiology of type 1 diabetes mellitus (T1DM) is still unknown; numerous studies are performed to unravel the environmental factors involved in triggering the disease. SLC11A1 is a membrane transporter that is expressed in late endosomes of antigen presenting cells involved in the immunopathogenic events leading to T1DM. …

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WebMar 27, 2024 · Age- and gender-dependent association of SLC11A1 polymorphisms with tuberculosis susceptibility ... we observed that the “C/C” genotype of rs4674301 was … WebSlc11a1 (formerly Nramp1) is a proton/divalent cation transporter that regulates cation homeostasis in macrophages. Slc11a2 mediates divalent cation uptake via the gut and delivery into cells. The mode of action of the two transporters remains controversial. Heterologous expression in frog oocytes shows Slc11a2 is a symporter, whereas Slc11a1 …

Web3'UTR of bovine SLC11A1 modulates gene expression and subsequent disease resistance in a phase dependent manner. The results of this study demonstrate that there are seventy-five total single nucleotide polymorphic (SNP) sites (excluding indels) located within the bovine genomic SLC11A1 sequence of a Brucella abortus resistant bull and a ... WebApr 1, 2013 · SLC11A1 is a 90–100 kDa integral transmembrane protein expressed in the lysosomal compartment of macrophages and in tertiary granules of neutrophils. The human SLC11A1 gene was cloned, and localized to the long arm of chromosome 2 (2q35).

Webof SLC11A1 gene is very important due to its association with resistance/ susceptibility to various intracellular pathogens in human as well as in livestock species. The SLC11A1 gene, formerly known as natural resistance-associated macrophage protein 1 (NRAMP1) encodes an integral membrane protein regulating the activity of macrophages. WebSLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family. Mutations in the SLC11A1 gene are involved in susceptibility to …

WebDec 7, 2007 · Slc11a1 (formerly Nramp1) is a proton/divalent cation transporter that regulates cation homeostasis in macrophages. Slc11a2 mediates divalent cation uptake via the gut and delivery into cells. The mode of action of the two transporters remains controversial. Heterologous expression in frog oocytes s …

WebJan 25, 2011 · Background Natural resistance associated macrophage protein 1 (NRAMP1), encoded by the SLC11A1 gene, has been described to regulate macrophage activation and be associated with infectious and autoimmune diseases. The relation between SLC11A1 polymorphisms and tuberculosis susceptibility has been studied in different populations. … bytefenceserviceWebIn addition, we observed that the CC genotype of rs4674301 was correlated with increased TB risk in females (p = 0.043). Our results demonstrated the relationships between polymorphisms (rs7608307, rs4674301, and rs13062) in or near the SLC11A1 gene and age- and sex-specific TB risk in the northwest Chinese Han population. clothotk locationWebMay 1, 2012 · SLC11A1 is a promising candidate gene to interpret sensitivity and resistance to intracellular pathogens including mycobacteria, because the murine Nramp1 gene was … byte fence serialzWebMar 9, 2024 · The Slc11a1 encodes a late endosomal/lysosomal protein/divalent cation transporter, which regulates iron homeostasis in macrophages. results demonstrate a … bytefence removeWebSLC11A1 (formerly Human natural resistance–associated macrophage protein 1 (NRAMP1)) has been associated with susceptibility to tuberculosis. 94 The importance of … cloth other termWebSolute carrier family 11a member 1 (Slc11a1; formerly natural resistance-associated macrophage protein 1) encodes a late endosomal/lysosomal protein/divalent cation transporter, which regulates iron homeostasis in macrophages. During macrophage activation, Slc11a1 exerts pleiotropic effects on gene … bytefence serviceWebCurrent and future radar maps for assessing areas of precipitation, type, and intensity. Currently Viewing. RealVue™ Satellite. See a real view of Earth from space, providing a … bytefetch alton